What is PAV?

PAV stands for post-antibiotic vulvovaginitis. This randomised double-blind controlled trial is testing whether oral and /or vaginal lactobacillus can prevent thrush when women take antibiotics.

Trial results

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The PAV trial was finished in July 2003 on advice of the independent Data Monitoring Committee. At this time, 278 women had kindly taken part in the study.

The results were that the women taking either the oral or vaginal lactobacillus (or both) were as likely to develop thrush while taking antibiotics as the women taking the placebo medications.

If you would like to read more about the trial results, try these links:

1. for the full paper published in the British Medical Journal:
   1. Effect of lactobacillus in preventing post-antibiotic vulvovaginal candidiasis: a randomised controlled trial
2. for the view of ABC Science Online:
   1. News in Science - Yoghurt a dud for thrush? - 27/08/2004
   2. Transcript of the interview with Norman Swan on the Health Report - 30/08/2004
      
      

Contact Us

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PAV Study
Department of General Practice
The University of Melbourne
200 Berkeley Street
Carlton 3053

PHONE: 03 8344 9723
FAX: (03) 9347 6136
EMAIL: dgp-pav@unimelb.edu.au
WEBSITE: http://www.pav.unimelb.edu.au